Research Topic

T-cell and B-cell Immunology

This cluster of papers focuses on the development, function, and regulation of regulatory T cells (Tregs), particularly emphasizing the role of transcription factor Foxp3, TGF-ß induction, immune tolerance, thymic selection, memory T cells, IL-2 signaling, and their involvement in tumor immunity and immunological surveillance. The cluster also explores the implications of Tregs in autoimmunity and their potential for therapeutic interventions.