Secoisolariciresinol diglucoside: a potent multifarious bioactive phytoestrogen of flaxseed.

TL;DRAbstract

Currently, there is a great focus on the relation between diet and degenerative diseases. Epidemiol. studies have proved that lignan-rich diets help reduce risk of various hormone-dependent cancers, heart disease and osteoporosis. Lignans are another group of diphenolic compds. or phytoestrogens which are less investigated and are present in a wide variety of plants. Considering the health beneficial potential of food components, lignans are also becoming an interesting topic and consumption of lignan-rich foods are studied for their putative health beneficial effects on human health. Flaxseed is the richest plant source of lignans and omega-3 fatty acid (ALA). Secoisolariciresinol diglucoside (SDG) is the principal and prospective bioactive lignan present in flaxseed. When ingested in relatively large amts., it is converted to Secoisolariciresinol (SECO), which is further metabolized to the mammalian lignans enterodiol (ED) and enterolactone (EL) in the large bowel by the action of gu

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