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Open AccessArticle10.3748/wjg.v9.i7.1571

Maxizyme-mediated specific inhibition on mutant-type p53<i>in vitro</i>

Xinjuan Kong-2003-01-01-World Journal of Gastroenterology

TL;DRAbstract

pU6Mz had a specific catalytic activity against mtp53 in cell-free system. These lay a good foundation for studying the effects of anti-mtp53 maxizyme in HCC cell lines. The results suggest that maxizyme may be a promising alternative approach for treating hepatocellular carcinoma containing mtp53.

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pU6Mz had a specific catalytic activity against mtp53 in cell-free system. These lay a good foundation for studying the effects of anti-mtp53 maxizyme in HCC cell lines. The results suggest that maxizyme may be a promising alternative approach for treating hepatocellular carcinoma containing mtp53.

Keywords

Molecular biologyBiologyMutantRecombinant DNACell cultureIn vitroEndonucleaseGene

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