Abstract 51: Degree of Clot Enhancement on Admission CT Predicts Revascularization Efficacy in Acute Ischemic Stroke

TL;DRAbstract

Background: Thrombi in the setting of acute ischemic stroke have been classified in pathology studies as “red clots” (erythrocyte rich) versus “white clots” (platelet/fibrin rich). Current strategies in lysing these clots include pharmacological agents and mechanical devices. Despite these treatment options, thrombolysis fails in a significant portion of patients and may lead to hemorrhagic complications. Having insight into the clot composition may provide clinicians with a way to triage patients to the appropriate treatment. The purpose of the study was to investigate whether the lysability of thrombi in acute ischemic stroke can be predicted by measuring the Hounsfield (HU) on the admission non-contrast CT (NCT), post-contrast enhanced CT (CECT) and CTA. Methods: We studied 53 patients with acute anterior and posterior circulation large vessel ischemic strokes treated at our institution with IV tPA, IA tPA, and/or mechanical thrombectomy devices (Merci). The HU of the clot was measu

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