TL;DRAbstract
Uganda has the largest pig population in east Africa, and most of the animals are owned by smallholders. Infectious diseases among pigs have a devastating impact on the livelihood of these farmers, which are dependent on the proceeds from pig rearing. In a metagenomics study of the wild pig species bushpig (Potamochoerus larvatus), the porcine viruses Torque teno sus virus (TTSuV) 1and 2 and Porcine parvovirus 4 (PPV4) were detected. TTSuV1 and 2 are ubiquitous in the world’s swine population, and PPV4 has been found in USA and China, but neither of them has been studied in Africa previously. The pathogenic properties of these viruses are unknown. The aim of this project was to do a first estimate of the prevalence of these viruses in pigs in Uganda, and to genetically characterize viruses detected in samples from bushpigs. The prevalence studies were made on serum samples from domestic pigs using PCR with genotype specific primers for TTSuV and PPV4 primers designed from the bushpig P
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Uganda has the largest pig population in east Africa, and most of the animals are owned by smallholders. Infectious diseases among pigs have a devastating impact on the livelihood of these farmers, which are dependent on the proceeds from pig rearing. In a metagenomics study of the wild pig species bushpig (Potamochoerus larvatus), the porcine viruses Torque teno sus virus (TTSuV) 1and 2 and Porcine parvovirus 4 (PPV4) were detected. TTSuV1 and 2 are ubiquitous in the world’s swine population, and PPV4 has been found in USA and China, but neither of them has been studied in Africa previously. The pathogenic properties of these viruses are unknown. The aim of this project was to do a first estimate of the prevalence of these viruses in pigs in Uganda, and to genetically characterize viruses detected in samples from bushpigs. The prevalence studies were made on serum samples from domestic pigs using PCR with genotype specific primers for TTSuV and PPV4 primers designed from the bushpig P
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