LYSOLECITHINS AND LYSOCEPHALINS

TL;DRAbstract

In a previous publication,' Levene and Rolf showed that by the action of cobra venom on egg yolk a product is formed which consists of a mixture of lysolecithin and lysocephalin.The evidence available at the time was to a certain extent of indirect character.In order to furnish more conclusive proof of this assumption it was necessary to isolate the components.This isolation is now accomplished.In several other respecm also, the preparation of lysolecithin and lysocephalin was important.To begin with, the physical properties, especially the solubilities of these substances, are such as to permit a fairly accurate determination of their dissociation constants.The latter ought to be practically the same for the lyso derivatives as for the parent substances.It is possible that a rational method of separation based on the dissociation constants might be devised for the lyso derivatives, and then successfully applied to the separation of cephalin from lecithin.Up to date, the latter problem

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