Harmlessness of 1 mg cefuroxime intracameral injection at the end of cataract surgery

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Abstract Purpose Intracameral 1mg cefuroxime injection at the end of cataract surgery is included in the good practice in France and a lot of countries. Few studies have shown a macular toxicity for high doses of cefuroxime in particular in a case of dilution error for exemple. Methods We propose a study on 18, of simple cataract operated, eyes : by phakoemulsification, the same surgeon, without particular surgical complications, and no posterior capsule rupture. Only patients with medium cataract and a normal macula were included in the study. A time‐domain macular OCT was pre‐operatively made, and then at 7 and 30 post‐operative days. The principal criterion of judgement was the central macular thickness at 30 post‐operative days. Results The average pre‐operative central macular thickness was 209,11 +/‐ 29,44 microns (143‐279), at 7 post‐operative days the average was 214,44 +/‐ 28,42 microns (145‐267), and at 30 post‐operative days was 219,44 +/‐ 27,41 microns (145‐253). The differ

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