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Dynamical properties of interfacial water and its role for biomolecular dynamics

Helén Jansson-2006-01-01-Chalmers Publication Library (Chalmers University of Technology)
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TL;DRAbstract

Water is the foundation of life, and without it life as we know it would not exist. An organism consists to a large extent of water, and apart from a few larger reservoirs, a large fraction of the water in a body is closely associated with surfaces of biomolecules of different kinds. This water is denoted biological water. The biological water is known to affect the dynamics of biomaterials such as proteins, which in turn is necessary for their functions. However, how and why the surrounding environment affects the dynamics of proteins and other biomolecules is still not fully understood. Therefore, it is of importance to investigate not only the dynamics of the biomolecules but also the dynamics of their surrounding solvent and how they are related. We have investigated systems with water associated to surfaces of different kinds, both a model system and in various biological systems. In addition, measurements on proteins in solvents of different viscosities and dynamical properties h

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Water is the foundation of life, and without it life as we know it would not exist. An organism consists to a large extent of water, and apart from a few larger reservoirs, a large fraction of the water in a body is closely associated with surfaces of biomolecules of different kinds. This water is denoted biological water. The biological water is known to affect the dynamics of biomaterials such as proteins, which in turn is necessary for their functions. However, how and why the surrounding environment affects the dynamics of proteins and other biomolecules is still not fully understood. Therefore, it is of importance to investigate not only the dynamics of the biomolecules but also the dynamics of their surrounding solvent and how they are related. We have investigated systems with water associated to surfaces of different kinds, both a model system and in various biological systems. In addition, measurements on proteins in solvents of different viscosities and dynamical properties h

Keywords

BiomoleculeChemical physicsDynamics (music)Arrhenius equationMolecular dynamicsBiological systemChemistryNanotechnology

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