Article
Protein and mRNA expression of notch pathway components in operable tumors of patients with laryngeal cancer.
Dimitrios Krikelis,Vassiliki Kotoula,Mattheos Bobos,Elena Fountzilas,Konstantinos Markou,Ilias Karasmanis+5 more-2014-11-01-PubMed
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TL;DRAbstract
Our study indicates a consistent unfavorable effect of Notch3 and cytoplasmic Jagged1 protein expression, a favorable impact of nuclear Jagged 1 localization, and a differential prognostic value of Notch2 expression according to the presence of cytoplasmic Jagged 1.
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Our study indicates a consistent unfavorable effect of Notch3 and cytoplasmic Jagged1 protein expression, a favorable impact of nuclear Jagged 1 localization, and a differential prognostic value of Notch2 expression according to the presence of cytoplasmic Jagged 1.
Keywords
Tissue microarrayImmunohistochemistryNotch signaling pathwayHazard ratioPathologyBiologyCancerMessenger RNA
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