Investigation into alternatives to fetal calf serum in animal cell culture

TL;DRAbstract

Mammalian cell culture has wide and expanding applications in both research and biotechnological/pharmaceutical industries The development and routine use of serum-free media (SFM) is a high priority for cell culture from both an industrial and scientific point of view as evidenced by the literature and the ever increasing supply of commercial preparations designed to bulk up growth in serum-free systems Production of vaccines, therapeutics and monoclonal antibodies for diagnostic and therapeutic purposes are just some of the many applications in which mammalian cell culture can dominate.
\n
\nFor cell culture products to be of diagnostic and therapeutic use, the quahty o f these biomaterials need to meet the highest standards In addition to precise process control during isolation of the product, the milieu in which the cells are active is of prime importance.
\n
\nThe complexity and undefined nature of serum has been recognised for some time Several approaches have be

Chat with Paper

AI Agents for this Paper