New sensitive methods for the spectrophotometric determination of some catecholamine derivatives
TL;DRAbstract
Rapid, simple, and sensitive spectrophotometric methods for the detn. of pyrocatechol, dopamine hydrochloride, levo dopa, Me dopa, and adrenaline hydrochloride in either pure form or its pharmaceutical prepns. is described. The 1st method is based on the interaction of catecholamine derivs. with iron(III) and subsequent reaction with ferricyanide in presence of hydrochloric acid medium to yield prussian blue colored complex with I»max of 730 nm. In the 2nd method, the interaction of nitrite ions with the catecholamines in neutral medium in presence of aluminum ions to yield a red product in alk. medium with I»max of 500-510 nm. The optical characteristics, interference studies and application to pharmaceutical prepns. were reported. [on SciFinder(R)]
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Rapid, simple, and sensitive spectrophotometric methods for the detn. of pyrocatechol, dopamine hydrochloride, levo dopa, Me dopa, and adrenaline hydrochloride in either pure form or its pharmaceutical prepns. is described. The 1st method is based on the interaction of catecholamine derivs. with iron(III) and subsequent reaction with ferricyanide in presence of hydrochloric acid medium to yield prussian blue colored complex with I»max of 730 nm. In the 2nd method, the interaction of nitrite ions with the catecholamines in neutral medium in presence of aluminum ions to yield a red product in alk. medium with I»max of 500-510 nm. The optical characteristics, interference studies and application to pharmaceutical prepns. were reported. [on SciFinder(R)]
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