In Silico Bioreactors for the Computer-Aided Design of Tissue Engineering Applications

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In Silico Bioreactors for the Computer-Aided Design of Tissue Engineering Applications

Filippo Consolo,Laura Gaetano,Giacomo Di Benedetto,C. Anthony Hunt,Umberto Morbiducci,Franco Maria Montevecchi-2010-01-01-PORTO Publications Open Repository TOrino (Politecnico di Torino)

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TL;DRAbstract

Tissue engineering (TE) is an emerging multidisciplinary field that draws on expertise from medicine, biology, chemistry, genetics, engineering, computer and life science. Its mission is to discover solutions to one of the most challenging medical problems faced by humans: replace tissue and organ functions when damage is beyond natural recovery process. A precondition for successful TE is having an adequate understanding of the principles of tissue genesis. The goal is to apply that knowledge to produce functional tissue replacements suitable for clinical use. Specifically achieve biological-inspired, biocompatible, tissue-mimetic structures that, when implanted in vivo, restore or improve failed or compromised human tissue and/or organ function. Impressive progress in human tissue regeneration followed development and implementation of advanced technologies that enabled better understanding and control signalling within microenvironments during growth and maturation of tissue functio

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Tissue engineering (TE) is an emerging multidisciplinary field that draws on expertise from medicine, biology, chemistry, genetics, engineering, computer and life science. Its mission is to discover solutions to one of the most challenging medical problems faced by humans: replace tissue and organ functions when damage is beyond natural recovery process. A precondition for successful TE is having an adequate understanding of the principles of tissue genesis. The goal is to apply that knowledge to produce functional tissue replacements suitable for clinical use. Specifically achieve biological-inspired, biocompatible, tissue-mimetic structures that, when implanted in vivo, restore or improve failed or compromised human tissue and/or organ function. Impressive progress in human tissue regeneration followed development and implementation of advanced technologies that enabled better understanding and control signalling within microenvironments during growth and maturation of tissue functio

Keywords

Computer Aided DesignBioreactorIn silicoTissue engineeringComputer scienceBiochemical engineeringEngineeringEngineering drawing

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