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In his celebrated book entitled Experiments and Observations on the Gastric juice and the Physiology of Digestion 1 William Beaumont precisely describes duodenogastric reflux of bile. While observing the stomach of his patient and experimental subject, Alexis St. Martin, across a gastric fistula, Beaumont noted: ‘on lying him horizontally on his back, pressing the hands upon the hepatic region, agitating a little and at the same time turning him to the left side, bright yellow bile appears to flow freely through the pylorus, and passes out through the tube. Sometimes it is found mixed with the gastric juice, without this operation. This is, however, seldom the case unless it has been excited by some other cause’. Anger, while reducing the secretion of gastric acid, ‘causes an influx of bile into the stomach which impairs its solvent properties.’ ‘Irritation of the pyloric extremity of the stomach with the end of the elastic tube or the bulb of the thermometer, generally occasions a flo
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In his celebrated book entitled Experiments and Observations on the Gastric juice and the Physiology of Digestion 1 William Beaumont precisely describes duodenogastric reflux of bile. While observing the stomach of his patient and experimental subject, Alexis St. Martin, across a gastric fistula, Beaumont noted: ‘on lying him horizontally on his back, pressing the hands upon the hepatic region, agitating a little and at the same time turning him to the left side, bright yellow bile appears to flow freely through the pylorus, and passes out through the tube. Sometimes it is found mixed with the gastric juice, without this operation. This is, however, seldom the case unless it has been excited by some other cause’. Anger, while reducing the secretion of gastric acid, ‘causes an influx of bile into the stomach which impairs its solvent properties.’ ‘Irritation of the pyloric extremity of the stomach with the end of the elastic tube or the bulb of the thermometer, generally occasions a flo
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