Phytochemical and bioactivities of Malaysian Artocarpus lowii king, a. Scortechinii king and a. Teysmanii miq.

TL;DRAbstract

Phytochemical studies of Artocarpus lowii King, A. scortechinii King and A. teysmanii Miq. have resulted in the isolation of four new compounds and eight known compounds. Three new compounds have been successfully isolated from A. lowii King, i.e 2',4'-dihydroxy-4-methoxy-3'-prenyldihydrochalcone, 2',3,4',4-tetrahydroxy-3'- prenylchalcone and 2-hydroxyparatocarpin C. Three known compounds were identified as cycloheterophyllin, 2',4',4-trihydroxy-3'-prenylchalcone and 4-hydroxylonchocarpin. Methylation of 2',4'-dihydroxy-4-methoxy-3'-prenyldihydrochalcone and 2',4',4- trihydroxy-3'-prenylchalcone gave 2',4',4-trimethoxy-3'-prenyldihydrochalcone and 2'-hydroxy-4',4-dimethoxy-3'-prenylchalcone, respectively while methylation of cycloheterophyllin gave mixtures of dimethoxy and trimethoxy derivatives. Acetylation of cycloheterophyllin afforded cycloheterophyllin diacetate. A new compound was isolated from A. scortechinii King and was identified as 2',4',5',5-tetrahydroxy-3-geranyl-7,8-(2,2

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