&lt;i&gt;Chlorella&lt;/i&gt; Virus PBCV-1 Replication Is Not Affected by Cytoskeletal Disruptors

doi:https://doi.org/10.1159/000150240

<i>Chlorella</i> Virus PBCV-1 Replication Is Not Affected by Cytoskeletal Disruptors

Joseph W. Nietfeldt,Kit Lee,James L. Van Etten-1992-01-01-Intervirology

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TL;DRAbstract

The majority, if not the entire life cycle, of the large dsDNA-containing algal virus PBCV-1 occurs in localized regions in the cytoplasm. Thirteen drugs that disrupt the cytoskeleton had no effect on PBCV-1 replication at concentrations which inhibited host growth. Therefore, host cytoskeletal elements do not appear to be important in PBCV-1 morphogenesis.

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The majority, if not the entire life cycle, of the large dsDNA-containing algal virus PBCV-1 occurs in localized regions in the cytoplasm. Thirteen drugs that disrupt the cytoskeleton had no effect on PBCV-1 replication at concentrations which inhibited host growth. Therefore, host cytoskeletal elements do not appear to be important in PBCV-1 morphogenesis.

Keywords

CytoskeletonCytoplasmVirusCell biologyBiologyViral replicationVirologyReplication (statistics)

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