Cutaneous Neuroblastic and Ganglion Cell Proliferations

TL;DRAbstract

Neuroblastoma is a malignant neoplasm of ­neural crest lineage, most often arising in the adrenal medulla, paraganglia, or sympathetic chain. Cutaneous neuroblastoma usually represents metastasis from a visceral primary. However, rare cutaneous neuroblastoma may develop de novo without an identifiable visceral tumor, possibly from heterotopic neural crest cells. Neuroblastoma represents the most primitive form in a family of neoplasms, which includes ganglioneuroma at the opposite, mature end of the spectrum.

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