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Open AccessArticle10.14341/probl200955337-39

Testosterone level in male patients with coronary heart disease and essential hypertension

A. Ya. Kravchenko,В. М. Провоторов-2009-06-15-Problems of Endocrinology

TL;DRAbstract

The study was undertaken to ascertain the prevalence of age-related androgen deficiency in patients with coronary heart disease (CHD) and essential hypertension under the age of 60 years and its association with some risk factors. The study covered 107 patients (mean age 50.2±7.2 years). Of them 35 patients had essential hypertension and 72 had CHD, angina on exertion. The blood concentrations of testosterone and cholesterol were measured; the presence and type of adiposity and the level of depression were determined. The mean level of testosterone in patients with CHD and essential hypertension (9.2±0.96 n/mol/l) corresponded to an androgen-deficient state. There was a direct correlation of testosterone concentrations with waist circumference and an inverse correlation with the levels of atherogenic lipoproteins and depression.

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The study was undertaken to ascertain the prevalence of age-related androgen deficiency in patients with coronary heart disease (CHD) and essential hypertension under the age of 60 years and its association with some risk factors. The study covered 107 patients (mean age 50.2±7.2 years). Of them 35 patients had essential hypertension and 72 had CHD, angina on exertion. The blood concentrations of testosterone and cholesterol were measured; the presence and type of adiposity and the level of depression were determined. The mean level of testosterone in patients with CHD and essential hypertension (9.2±0.96 n/mol/l) corresponded to an androgen-deficient state. There was a direct correlation of testosterone concentrations with waist circumference and an inverse correlation with the levels of atherogenic lipoproteins and depression.

Keywords

MedicineInternal medicineTestosterone (patch)Depression (economics)AndrogenEssential hypertensionWaistAngina

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