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Possible role of BNP for an early diagnosis of asymptomatic left ventricular dysfunction: a retrospective study.

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TL;DRAbstract

The sensitivity of BNP in the identification of patients with ALVD by adopting a cut-off of 156 pg/ml was equal to 83.7%, which is in keeping with the literature values. In case of programs targeted to ALVD screening, the choice of adopting a relatively low threshold value for BNP seems to comply with the goal of enhancing sensitivity , so as to exclude from the echocardiography the individuals found negative at BNP assay and thereby reduce the number of unnecessary echocardiographic examinations in individuals with low probability of having ALVD.

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The sensitivity of BNP in the identification of patients with ALVD by adopting a cut-off of 156 pg/ml was equal to 83.7%, which is in keeping with the literature values. In case of programs targeted to ALVD screening, the choice of adopting a relatively low threshold value for BNP seems to comply with the goal of enhancing sensitivity , so as to exclude from the echocardiography the individuals found negative at BNP assay and thereby reduce the number of unnecessary echocardiographic examinations in individuals with low probability of having ALVD.

Keywords

MedicineAsymptomaticEjection fractionInternal medicineCardiologyReceiver operating characteristicDiastoleDoppler echocardiography

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