Gallium-67 scanning for tumor diagnosis
TL;DRAbstract
When /sup 67/Ga was given free of carrier, it was found predominantly within the liver, spleen, kidney, and bone. The addition of stable Ga caused a progressive increase in relative concentration within the skeleton and a relative decrease in soft tissue concentration. Within the group of lymphomatous tumors /sup 67/Ga uptake appears to be highest in Hodgkin's disease with nodular sclerosis and lower in other lymphomas. Histiocytic cell types, including all mixed types of lymphoma, have a higher rate of positive scans than do lymphocytic types. Even in Hodgkin's disease group, a negative scan does not exclude disease. In the abdomen, scan results in the lymphomatous group are generally inferior to those reported for the chest. (HLW)
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When /sup 67/Ga was given free of carrier, it was found predominantly within the liver, spleen, kidney, and bone. The addition of stable Ga caused a progressive increase in relative concentration within the skeleton and a relative decrease in soft tissue concentration. Within the group of lymphomatous tumors /sup 67/Ga uptake appears to be highest in Hodgkin's disease with nodular sclerosis and lower in other lymphomas. Histiocytic cell types, including all mixed types of lymphoma, have a higher rate of positive scans than do lymphocytic types. Even in Hodgkin's disease group, a negative scan does not exclude disease. In the abdomen, scan results in the lymphomatous group are generally inferior to those reported for the chest. (HLW)
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