PBPK models for the prediction of in vivo performance of oral dosage forms
2013 · European Journal of Pharmaceutical Sciences · 313 citations
https://doi.org/10.1016/j.ejps.2013.09.008
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Aleksandra Galetin
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Aleksandra Galetin is an academic researcher from Manchester Academic Health Science Centre. The author has contributed to research in topics: Pharmacogenetics and Drug Metabolism & Drug Transport and Resistance Mechanisms & Pharmacological Effects and Toxicity Studies. The author has an h-index of 58, co-authored 210 publications.
ORCID: 0000-0002-3933-5217Papers by this author
worksPrediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data
2010 · Drug Metabolism and Disposition · 295 citations
https://doi.org/10.1124/dmd.110.032649
Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug‐Drug Interaction Evaluation: Perspectives From the International Transporter Consortium
2018 · Clinical Pharmacology & Therapeutics · 197 citations
https://doi.org/10.1002/cpt.1216
Membrane transporters in drug development and as determinants of precision medicine
2024 · Nature Reviews Drug Discovery · 189 citations
https://doi.org/10.1038/s41573-023-00877-1
PREDICTION OF TIME-DEPENDENT CYP3A4 DRUG-DRUG INTERACTIONS: IMPACT OF ENZYME DEGRADATION, PARALLEL ELIMINATION PATHWAYS, AND INTESTINAL INHIBITION
2005 · Drug Metabolism and Disposition · 161 citations
https://doi.org/10.1124/dmd.105.006874
Physiologically Based Pharmacokinetic Modeling of Intestinal First-Pass Metabolism of CYP3A Substrates with High Intestinal Extraction
2011 · Drug Metabolism and Disposition · 132 citations
https://doi.org/10.1124/dmd.111.039248
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