Membrane transporters in drug development
2010 · Nature Reviews Drug Discovery · 3,285 citations
https://doi.org/10.1038/nrd3028
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Xiaoyan Chu
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Xiaoyan Chu is an academic researcher from Merck & Co., Inc., Rahway, NJ, USA (United States). The author has contributed to research in topics: Drug Transport and Resistance Mechanisms & Pharmacological Effects and Toxicity Studies & Pharmacogenetics and Drug Metabolism. The author has an h-index of 47, co-authored 105 publications.
ORCID: 0000-0001-7223-9000Papers by this author
worksTransporters in Drug Development: 2018 ITC Recommendations for Transporters of Emerging Clinical Importance
2018 · Clinical Pharmacology & Therapeutics · 226 citations
https://doi.org/10.1002/cpt.1112
Clinical Probes and Endogenous Biomarkers as Substrates for Transporter Drug‐Drug Interaction Evaluation: Perspectives From the International Transporter Consortium
2018 · Clinical Pharmacology & Therapeutics · 197 citations
https://doi.org/10.1002/cpt.1216
Function and Expression of Multidrug Resistance-Associated Protein Family in Human Colon Adenocarcinoma Cells (Caco-2)
2000 · Journal of Pharmacology and Experimental Therapeutics · 192 citations
https://doi.org/10.1016/s0022-3565(24)35286-3
Membrane transporters in drug development and as determinants of precision medicine
2024 · Nature Reviews Drug Discovery · 189 citations
https://doi.org/10.1038/s41573-023-00877-1
Transport of the Dipeptidyl Peptidase-4 Inhibitor Sitagliptin by Human Organic Anion Transporter 3, Organic Anion Transporting Polypeptide 4C1, and Multidrug Resistance P-glycoprotein
2007 · Journal of Pharmacology and Experimental Therapeutics · 175 citations
https://doi.org/10.1124/jpet.106.116517
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