PREDICTION OF TIME-DEPENDENT CYP3A4 DRUG-DRUG INTERACTIONS: IMPACT OF ENZYME DEGRADATION, PARALLEL ELIMINATION PATHWAYS, AND INTESTINAL INHIBITION
2005 · Drug Metabolism and Disposition · 161 citations
https://doi.org/10.1124/dmd.105.006874
H
Howard Burt
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25
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838
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13
h-index
13
i10-index
Howard Burt is an academic researcher from Simcyp (United Kingdom). The author has contributed to research in topics: Pharmacogenetics and Drug Metabolism & Drug Transport and Resistance Mechanisms & Pharmacological Effects and Toxicity Studies. The author has an h-index of 13, co-authored 22 publications.
Papers by this author
worksMetformin and cimetidine: Physiologically based pharmacokinetic modelling to investigate transporter mediated drug–drug interactions
2016 · European Journal of Pharmaceutical Sciences · 118 citations
https://doi.org/10.1016/j.ejps.2016.03.020
Extrapolation of praziquantel pharmacokinetics to a pediatric population: a cautionary tale
2018 · Journal of Pharmacokinetics and Pharmacodynamics · 23 citations
https://doi.org/10.1007/s10928-018-9601-1
The nested enzyme-within-enterocyte (NEWE) turnover model for predicting dynamic drug and disease effects on the gut wall
2019 · European Journal of Pharmaceutical Sciences · 8 citations
https://doi.org/10.1016/j.ejps.2019.02.017
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