Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O <sub>2</sub> -Regulated Prolyl Hydroxylation
2001 · Science · 5,454 citations
https://doi.org/10.1126/science.1059796
C
Christopher J. Schofield
Claim or correct this author profile
Claim this profile or suggest corrections to the name, affiliation, bio, photo, or paper titles. Approved changes appear as verified CitedEvidence overlays.
1.3K
Papers
62.5K
Citations
112
h-index
697
i10-index
Christopher J. Schofield is an academic researcher from Mansfield University. The author has contributed to research in topics: Cancer, Hypoxia, and Metabolism & Epigenetics and DNA Methylation & Antibiotic Resistance in Bacteria. The author has an h-index of 112, co-authored 1110 publications.
ORCID: 0000-0002-0290-6565Papers by this author
worksC. elegans EGL-9 and Mammalian Homologs Define a Family of Dioxygenases that Regulate HIF by Prolyl Hydroxylation
2001 · Cell · 3,325 citations
https://doi.org/10.1016/s0092-8674(01)00507-4
Signalling hypoxia by HIF hydroxylases
2005 · Biochemical and Biophysical Research Communications · 339 citations
https://doi.org/10.1016/j.bbrc.2005.08.111
Physiological and biochemical aspects of hydroxylations and demethylations catalyzed by human 2-oxoglutarate oxygenases
2010 · Trends in Biochemical Sciences · 277 citations
https://doi.org/10.1016/j.tibs.2010.07.002
Structural and Mechanistic Studies on the Inhibition of the Hypoxia-inducible Transcription Factor Hydroxylases by Tricarboxylic Acid Cycle Intermediates
2006 · Journal of Biological Chemistry · 229 citations
https://doi.org/10.1074/jbc.m608337200
Arginine demethylation is catalysed by a subset of JmjC histone lysine demethylases
2016 · Nature Communications · 216 citations
https://doi.org/10.1038/ncomms11974
Research topics
topicsChat about Author
Papers
Chat
Click to start Chat