Structural and Mechanistic Studies on the Inhibition of the Hypoxia-inducible Transcription Factor Hydroxylases by Tricarboxylic Acid Cycle Intermediates
2006 · Journal of Biological Chemistry · 229 citations
https://doi.org/10.1074/jbc.m608337200
M
M.A. McDonough
Claim or correct this author profile
Claim this profile or suggest corrections to the name, affiliation, bio, photo, or paper titles. Approved changes appear as verified CitedEvidence overlays.
282
Papers
12.5K
Citations
55
h-index
127
i10-index
M.A. McDonough is an academic researcher. The author has contributed to research in topics: Cancer, Hypoxia, and Metabolism & Metal-Catalyzed Oxygenation Mechanisms & Epigenetics and DNA Methylation. The author has an h-index of 55, co-authored 240 publications.
ORCID: 0000-0003-4664-6942Papers by this author
worksStructural Basis for Inhibition of the Fat Mass and Obesity Associated Protein (FTO)
2013 · Journal of Medicinal Chemistry · 155 citations
https://doi.org/10.1021/jm400193d
Asparagine and Aspartate Hydroxylation of the Cytoskeletal Ankyrin Family Is Catalyzed by Factor-inhibiting Hypoxia-inducible Factor
2010 · Journal of Biological Chemistry · 73 citations
https://doi.org/10.1074/jbc.m110.193540
Aspartate/asparagine-β-hydroxylase crystal structures reveal an unexpected epidermal growth factor-like domain substrate disulfide pattern
2019 · Nature Communications · 50 citations
https://doi.org/10.1038/s41467-019-12711-7
In vitro selection of macrocyclic peptide inhibitors containing cyclic γ2,4-amino acids targeting the SARS-CoV-2 main protease
2023 · Nature Chemistry · 48 citations
https://doi.org/10.1038/s41557-023-01205-1
96-week retention in treatment with extended-release subcutaneous buprenorphine depot injections among people with opioid dependence: Extended follow-up after a single-arm trial
2024 · International Journal of Drug Policy · 15 citations
https://doi.org/10.1016/j.drugpo.2024.104390
Research topics
topicsChat about Author
Papers
Chat
Click to start Chat