The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
2005 · Biochemical Journal · 496 citations
https://doi.org/10.1042/bj20051180
M
Mária Deák
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Mária Deák is an academic researcher from Nestlé (Switzerland). The author has contributed to research in topics: Protein Kinase Regulation and GTPase Signaling & PI3K/AKT/mTOR signaling in cancer & Metabolism, Diabetes, and Cancer. The author has an h-index of 69, co-authored 100 publications.
Papers by this author
worksThe WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K+–Cl− co-transporters
2014 · Biochemical Journal · 212 citations
https://doi.org/10.1042/bj20131478
Regulation of activity and localization of the WNK1 protein kinase by hyperosmotic stress
2006 · The Journal of Cell Biology · 200 citations
https://doi.org/10.1083/jcb.200605093
Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways
2011 · Journal of Cell Science · 182 citations
https://doi.org/10.1242/jcs.077230
Mechanism of Action of Compound-13: An α1-Selective Small Molecule Activator of AMPK
2014 · Chemistry & Biology · 124 citations
https://doi.org/10.1016/j.chembiol.2014.05.014
Chemical genetic screen identifies Gapex-5/GAPVD1 and STBD1 as novel AMPK substrates
2019 · Cellular Signalling · 28 citations
https://doi.org/10.1016/j.cellsig.2019.02.001
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