Surface charge and hydrophobicity determine ErbB2 binding to the Hsp90 chaperone complex
2005 · Nature Structural & Molecular Biology · 154 citations
https://doi.org/10.1038/nsmb885
W
Wanping Xu
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Wanping Xu is an academic researcher from The University of Sydney. The author has contributed to research in topics: Heat shock proteins research & Ubiquitin and proteasome pathways & ATP Synthase and ATPases Research. The author has an h-index of 29, co-authored 46 publications.
Papers by this author
worksRegulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase
2009 · Proceedings of the National Academy of Sciences · 119 citations
https://doi.org/10.1073/pnas.0810571106
The heat shock protein 90 inhibitor geldanamycin and the ErbB inhibitor ZD1839 promote rapid PP1 phosphatase-dependent inactivation of AKT in ErbB2 overexpressing breast cancer cells.
2003 · PubMed · 94 citations
Hsp90, not Grp94, regulates the intracellular trafficking and stability of nascent ErbB2
2002 · Cell Stress and Chaperones · 79 citations
https://doi.org/10.1379/1466-1268(2002)007<0091:hngrti>2.0.co;2
Loss of Hsp90 Association Up-Regulates Src-Dependent ErbB2 Activity
2006 · Molecular and Cellular Biology · 62 citations
https://doi.org/10.1128/mcb.00899-06
Curcumin-induced degradation of ErbB2: A role for the E3 ubiquitin ligase CHIP and the Michael reaction acceptor activity of curcumin
2006 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · 59 citations
https://doi.org/10.1016/j.bbamcr.2006.11.004
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