Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1
2018 · Nature · 1,734 citations
https://doi.org/10.1038/nature25986
R
Richard G. Carroll
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Richard G. Carroll is an academic researcher from Royal College of Surgeons in Ireland. The author has contributed to research in topics: HIV Research and Treatment & Immune Cell Function and Interaction & CAR-T cell therapy research. The author has an h-index of 52, co-authored 83 publications.
ORCID: 0000-0001-9917-3443Papers by this author
worksCircadian clock protein BMAL1 regulates IL-1β in macrophages via NRF2
2018 · Proceedings of the National Academy of Sciences · 340 citations
https://doi.org/10.1073/pnas.1800431115
Treatment of Advanced Leukemia in Mice with mRNA Engineered T Cells
2011 · Human Gene Therapy · 217 citations
https://doi.org/10.1089/hum.2011.070
An unexpected link between fatty acid synthase and cholesterol synthesis in proinflammatory macrophage activation
2018 · Journal of Biological Chemistry · 186 citations
https://doi.org/10.1074/jbc.ra118.001921
Parkin Sensitizes toward Apoptosis Induced by Mitochondrial Depolarization through Promoting Degradation of Mcl-1
2014 · Cell Reports · 142 citations
https://doi.org/10.1016/j.celrep.2014.10.046
Intrinsic resistance to T cell infection with HIV type 1 induced by CD28 costimulation
1997 · The Journal of Immunology · 76 citations
https://doi.org/10.4049/jimmunol.158.11.5545
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