Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins
2014 · Genome Research · 1,853 citations
https://doi.org/10.1101/gr.171322.113
D
Daesik Kim
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Daesik Kim is an academic researcher from Seoul National University. The author has contributed to research in topics: CRISPR and Genetic Engineering & RNA and protein synthesis mechanisms & RNA regulation and disease. The author has an h-index of 37, co-authored 146 publications.
ORCID: 0000-0003-0806-5979Papers by this author
worksIn vivo genome editing with a small Cas9 orthologue derived from Campylobacter jejuni
2017 · Nature Communications · 725 citations
https://doi.org/10.1038/ncomms14500
Directed evolution of CRISPR-Cas9 to increase its specificity
2018 · Nature Communications · 525 citations
https://doi.org/10.1038/s41467-018-05477-x
Evaluating and Enhancing Target Specificity of Gene-Editing Nucleases and Deaminases
2019 · Annual Review of Biochemistry · 169 citations
https://doi.org/10.1146/annurev-biochem-013118-111730
Unbiased investigation of specificities of prime editing systems in human cells
2020 · Nucleic Acids Research · 152 citations
https://doi.org/10.1093/nar/gkaa764
CRISPR-Cas9–mediated therapeutic editing of <i>Rpe65</i> ameliorates the disease phenotypes in a mouse model of Leber congenital amaurosis
2019 · Science Advances · 100 citations
https://doi.org/10.1126/sciadv.aax1210
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