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Pamela A. Lochhead

The Francis Crick Institute(GB)

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25

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2.0K

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20

h-index

22

i10-index

Pamela A. Lochhead is an academic researcher from The Francis Crick Institute. The author has contributed to research in topics: Ubiquitin and proteasome pathways & Melanoma and MAPK Pathways & Protein Kinase Regulation and GTPase Signaling. The author has an h-index of 20, co-authored 22 publications.

ORCID: 0000-0001-7498-0177

Research Topics

Ubiquitin and proteasome pathways Melanoma and MAPK Pathways Protein Kinase Regulation and GTPase Signaling FOXO transcription factor regulation Computational Drug Discovery Methods

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Activation-Loop Autophosphorylation Is Mediated by a Novel Transitional Intermediate Form of DYRKs

2005 · Cell · 320 citations

https://doi.org/10.1016/j.cell.2005.03.034

Pamela A. Lochhead Gary Sibbet Nick Morrice Vaughn Cleghon

A Chaperone-Dependent GSK3β Transitional Intermediate Mediates Activation-Loop Autophosphorylation

2006 · Molecular Cell · 272 citations

https://doi.org/10.1016/j.molcel.2006.10.009

Pamela A. Lochhead Ross Kinstrie Gary Sibbet Teeara Rawjee

Research topics

topics

Ubiquitin and proteasome pathways

Melanoma and MAPK Pathways

Protein Kinase Regulation and GTPase Signaling

FOXO transcription factor regulation

Computational Drug Discovery Methods

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