Inhibiting the Hedgehog Pathway in Patients with the Basal-Cell Nevus Syndrome
2012 · New England Journal of Medicine · 544 citations
https://doi.org/10.1056/nejmoa1113538
M
Michelle Aszterbaum
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Michelle Aszterbaum is an academic researcher. The author has contributed to research in topics: Hedgehog Signaling Pathway Studies & Genetic and rare skin diseases. & Cancer and Skin Lesions. The author has an h-index of 21, co-authored 28 publications.
ORCID: 0000-0002-6126-7644Papers by this author
worksIdentification of Mutations in the Human PATCHED Gene in Sporadic Basal Cell Carcinomas and in Patients with the Basal Cell Nevus Syndrome
1998 · Journal of Investigative Dermatology · 307 citations
https://doi.org/10.1046/j.1523-1747.1998.00222.x
Inhibition of the hedgehog pathway in patients with basal-cell nevus syndrome: final results from the multicentre, randomised, double-blind, placebo-controlled, phase 2 trial
2016 · The Lancet Oncology · 134 citations
https://doi.org/10.1016/s1470-2045(16)30566-6
Basal Cell Carcinoma Chemoprevention with Nonsteroidal Anti-inflammatory Drugs in Genetically Predisposed <i>PTCH1</i> +/− Humans and Mice
2010 · Cancer Prevention Research · 83 citations
https://doi.org/10.1158/1940-6207.capr-09-0200
Long‐term establishment, characterization and manipulation of cell lines from mouse basal cell carcinoma tumors
2006 · Experimental Dermatology · 73 citations
https://doi.org/10.1111/j.1600-0625.2006.00465.x
Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/– mice
2004 · Journal of Clinical Investigation · 66 citations
https://doi.org/10.1172/jci20732
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