Inhibiting the Hedgehog Pathway in Patients with the Basal-Cell Nevus Syndrome
2012 · New England Journal of Medicine · 544 citations
https://doi.org/10.1056/nejmoa1113538
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Jean Y. Tang
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Jean Y. Tang is an academic researcher from Stanford University. The author has contributed to research in topics: Hedgehog Signaling Pathway Studies & Skin and Cellular Biology Research & Nonmelanoma Skin Cancer Studies. The author has an h-index of 55, co-authored 248 publications.
ORCID: 0000-0002-5510-6502Papers by this author
worksSmoothened Variants Explain the Majority of Drug Resistance in Basal Cell Carcinoma
2015 · Cancer Cell · 415 citations
https://doi.org/10.1016/j.ccell.2015.02.002
Genomic Analysis of Smoothened Inhibitor Resistance in Basal Cell Carcinoma
2015 · Cancer Cell · 384 citations
https://doi.org/10.1016/j.ccell.2015.02.001
Itraconazole and Arsenic Trioxide Inhibit Hedgehog Pathway Activation and Tumor Growth Associated with Acquired Resistance to Smoothened Antagonists
2013 · Cancer Cell · 329 citations
https://doi.org/10.1016/j.ccr.2012.11.017
Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition
2014 · Nature Medicine · 312 citations
https://doi.org/10.1038/nm.3613
Open-Label, Exploratory Phase II Trial of Oral Itraconazole for the Treatment of Basal Cell Carcinoma
2014 · Journal of Clinical Oncology · 278 citations
https://doi.org/10.1200/jco.2013.49.9525
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