An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
2014 · Science · 802 citations
https://doi.org/10.1126/science.1259037
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Adam D. Durbin
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Adam D. Durbin is an academic researcher from St. Jude Children's Research Hospital. The author has contributed to research in topics: Neuroblastoma Research and Treatments & Protein Degradation and Inhibitors & Sarcoma Diagnosis and Treatment. The author has an h-index of 26, co-authored 126 publications.
ORCID: 0000-0002-5472-9847Papers by this author
worksASCL1 is a MYCN- and LMO1-dependent member of the adrenergic neuroblastoma core regulatory circuitry
2019 · Nature Communications · 95 citations
https://doi.org/10.1038/s41467-019-13515-5
Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q
2020 · Cell Reports · 58 citations
https://doi.org/10.1016/j.celrep.2020.108493
A CRISPR-drug perturbational map for identifying compounds to combine with commonly used chemotherapeutics
2023 · Nature Communications · 20 citations
https://doi.org/10.1038/s41467-023-43134-0
Group 3 medulloblastoma transcriptional networks collapse under domain specific EP300/CBP inhibition
2024 · Nature Communications · 12 citations
https://doi.org/10.1038/s41467-024-47102-0
STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
2024 · Cell Reports Medicine · 8 citations
https://doi.org/10.1016/j.xcrm.2024.101472
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