Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation
2022 · Nature Communications · 101 citations
https://doi.org/10.1038/s41467-022-29368-4
T
Thomas A. Leonard
Max Perutz Labs(AT)
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Thomas A. Leonard is an academic researcher from Max Perutz Labs. The author has contributed to research in topics: Protein Kinase Regulation and GTPase Signaling & PI3K/AKT/mTOR signaling in cancer & Cellular transport and secretion. The author has an h-index of 23, co-authored 87 publications.
ORCID: 0000-0001-6853-666XPapers by this author
worksA molecular ruler regulates cytoskeletal remodelling by the Rho kinases
2015 · Nature Communications · 73 citations
https://doi.org/10.1038/ncomms10029
Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase
2023 · Structure · 7 citations
https://doi.org/10.1016/j.str.2023.02.002
PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor
2025 · Proceedings of the National Academy of Sciences · 2 citations
https://doi.org/10.1073/pnas.2417218122
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