Differential GLP-1R Binding and Activation by Peptide and Non-peptide Agonists
2020 · Molecular Cell · 212 citations
https://doi.org/10.1016/j.molcel.2020.09.020
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Peishen Zhao
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Peishen Zhao is an academic researcher from Discovery Institute. The author has contributed to research in topics: Receptor Mechanisms and Signaling & Neuropeptides and Animal Physiology & Diabetes Treatment and Management. The author has an h-index of 27, co-authored 59 publications.
ORCID: 0000-0003-0185-0595Papers by this author
worksNeutrophil Elastase Activates Protease-activated Receptor-2 (PAR2) and Transient Receptor Potential Vanilloid 4 (TRPV4) to Cause Inflammation and Pain
2015 · Journal of Biological Chemistry · 163 citations
https://doi.org/10.1074/jbc.m115.642736
Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure Determination
2018 · ACS Pharmacology & Translational Science · 149 citations
https://doi.org/10.1021/acsptsci.8b00017
Toward a Structural Understanding of Class B GPCR Peptide Binding and Activation
2020 · Molecular Cell · 122 citations
https://doi.org/10.1016/j.molcel.2020.01.012
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation
2022 · Nature Communications · 77 citations
https://doi.org/10.1038/s41467-021-27760-0
Agonist-biased Trafficking of Somatostatin Receptor 2A in Enteric Neurons
2013 · Journal of Biological Chemistry · 36 citations
https://doi.org/10.1074/jbc.m113.496414
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