Cryo-EM structure of the active, Gs-protein complexed, human CGRP receptor
2018 · Nature · 257 citations
https://doi.org/10.1038/s41586-018-0535-y
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Giuseppe Deganutti
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Giuseppe Deganutti is an academic researcher from Coventry University. The author has contributed to research in topics: Receptor Mechanisms and Signaling & Neuropeptides and Animal Physiology & Protein Structure and Dynamics. The author has an h-index of 21, co-authored 98 publications.
ORCID: 0000-0001-8780-2986Papers by this author
worksStructure and Dynamics of Adrenomedullin Receptors AM<sub>1</sub> and AM<sub>2</sub> Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins
2020 · ACS Pharmacology & Translational Science · 98 citations
https://doi.org/10.1021/acsptsci.9b00080
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification
2023 · Nature Genetics · 95 citations
https://doi.org/10.1038/s41588-023-01462-3
Molecular Signature for Receptor Engagement in the Metabolic Peptide Hormone Amylin
2018 · ACS Pharmacology & Translational Science · 77 citations
https://doi.org/10.1021/acsptsci.8b00002
Dynamics of GLP-1R peptide agonist engagement are correlated with kinetics of G protein activation
2022 · Nature Communications · 77 citations
https://doi.org/10.1038/s41467-021-27760-0
Structure and dynamics of the active Gs-coupled human secretin receptor
2020 · Nature Communications · 68 citations
https://doi.org/10.1038/s41467-020-17791-4
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