Structural Asymmetry of AcrB Trimer Suggests a Peristaltic Pump Mechanism
2006 · Science · 584 citations
https://doi.org/10.1126/science.1131542
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Kay Diederichs
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Kay Diederichs is an academic researcher from University of Konstanz. The author has contributed to research in topics: Enzyme Structure and Function & DNA and Nucleic Acid Chemistry & Protein Structure and Dynamics. The author has an h-index of 66, co-authored 302 publications.
ORCID: 0000-0001-5360-0905Papers by this author
worksTransport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
2012 · Proceedings of the National Academy of Sciences · 339 citations
https://doi.org/10.1073/pnas.1114944109
Crystal structure of MalK, the ATPase subunit of the trehalose/maltose ABC transporter of the archaeon Thermococcus litoralis
2000 · The EMBO Journal · 309 citations
https://doi.org/10.1093/emboj/19.22.5951
Engineered disulfide bonds support the functional rotation mechanism of multidrug efflux pump AcrB
2008 · Nature Structural & Molecular Biology · 151 citations
https://doi.org/10.1038/nsmb.1379
Yeast d -Amino Acid Oxidase: Structural Basis of its Catalytic Properties
2002 · Journal of Molecular Biology · 128 citations
https://doi.org/10.1016/s0022-2836(02)01062-8
Structural and Kinetic Analysis of Bacillus subtilis N-Acetylglucosaminidase Reveals a Unique Asp-His Dyad Mechanism
2010 · Journal of Biological Chemistry · 119 citations
https://doi.org/10.1074/jbc.m110.131037
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