Identification of a Primary Target of Thalidomide Teratogenicity
2010 · Science · 2,031 citations
https://doi.org/10.1126/science.1177319
T
Takumi Ito
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Takumi Ito is an academic researcher from Kyushu Dental University. The author has contributed to research in topics: Multiple Myeloma Research and Treatments & Protein Degradation and Inhibitors & Ubiquitin and proteasome pathways. The author has an h-index of 29, co-authored 105 publications.
ORCID: 0000-0002-9997-2664Papers by this author
worksCereblon is a direct protein target for immunomodulatory and antiproliferative activities of lenalidomide and pomalidomide
2012 · Leukemia · 783 citations
https://doi.org/10.1038/leu.2012.119
Structural basis of thalidomide enantiomer binding to cereblon
2018 · Scientific Reports · 119 citations
https://doi.org/10.1038/s41598-018-19202-7
Exploiting ubiquitin ligase cereblon as a target for small-molecule compounds in medicine and chemical biology
2021 · Cell chemical biology · 52 citations
https://doi.org/10.1016/j.chembiol.2021.04.012
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