Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
2011 · Nature · 1,743 citations
https://doi.org/10.1038/nature10602
L
Leonard Guarente
IIT@MIT(US)
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Leonard Guarente is an academic researcher from IIT@MIT. The author has contributed to research in topics: Sirtuins and Resveratrol in Medicine & Adipose Tissue and Metabolism & Genetics, Aging, and Longevity in Model Organisms. The author has an h-index of 117, co-authored 225 publications.
ORCID: 0000-0003-4064-2510Papers by this author
worksThe NAD+-Dependent Deacetylase SIRT1 Modulates CLOCK-Mediated Chromatin Remodeling and Circadian Control
2008 · Cell · 1,392 citations
https://doi.org/10.1016/j.cell.2008.07.002
SIRT1 and other sirtuins in metabolism
2014 · Trends in Endocrinology and Metabolism · 1,102 citations
https://doi.org/10.1016/j.tem.2013.12.001
Sirt1 Mediates Neuroprotection from Mutant Huntingtin by Activation of TORC1 and CREB Transcriptional Pathway
2012 · Digital Access to Scholarship at Harvard (DASH) (Harvard University) · 365 citations
https://doi.org/10.1038/nm.2559
Repeat dose NRPT (nicotinamide riboside and pterostilbene) increases NAD+ levels in humans safely and sustainably: a randomized, double-blind, placebo-controlled study
2017 · npj Aging and Mechanisms of Disease · 180 citations
https://doi.org/10.1038/s41514-017-0016-9
Effects of Mutations in DNA Repair Genes on Formation of Ribosomal DNA Circles and Life Span in <i>Saccharomyces cerevisiae</i>
1999 · Molecular and Cellular Biology · 157 citations
https://doi.org/10.1128/mcb.19.5.3848
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