Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis
2020 · Journal of Experimental & Clinical Cancer Research · 222 citations
https://doi.org/10.1186/s13046-020-1528-x
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Jie Zhang is an academic researcher from Chinese Academy of Medical Sciences & Peking Union Medical College. The author has contributed to research in topics: Cancer Immunotherapy and Biomarkers & Cancer, Lipids, and Metabolism & RNA modifications and cancer. The author has an h-index of 47, co-authored 473 publications.
ORCID: 0009-0004-7346-8541Papers by this author
worksCholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans
2019 · Gut · 184 citations
https://doi.org/10.1136/gutjnl-2018-317581
Targeting fatty acid synthase modulates sensitivity of hepatocellular carcinoma to sorafenib via ferroptosis
2023 · Journal of Experimental & Clinical Cancer Research · 147 citations
https://doi.org/10.1186/s13046-022-02567-z
Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance
2021 · Nature Communications · 140 citations
https://doi.org/10.1038/s41467-021-27349-7
<p>Association Between Body Composition and Frailty in Elder Inpatients</p>
2020 · Clinical Interventions in Aging · 111 citations
https://doi.org/10.2147/cia.s243211
PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma
2019 · Journal of Experimental & Clinical Cancer Research · 104 citations
https://doi.org/10.1186/s13046-019-1194-z
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