Development of a Polo-like Kinase-1 Polo-Box Domain Inhibitor as a Tumor Growth Suppressor in Mice Models
2020 · Journal of Medicinal Chemistry · 21 citations
https://doi.org/10.1021/acs.jmedchem.0c01451
M
Mija Ahn
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Mija Ahn is an academic researcher from Korea Basic Science Institute. The author has contributed to research in topics: Microtubule and mitosis dynamics & Antimicrobial Peptides and Activities & Chemical Synthesis and Analysis. The author has an h-index of 17, co-authored 33 publications.
Papers by this author
worksConcentration-response curves of LPS neutralization by the peptides, as determined by LAL assay.
2015 · Figshare · 0 citations
https://doi.org/10.1371/journal.pone.0080025.g004
Modeled structure of Plk1-PBD in complex with bg-34; the model shows the presence of the phosphate-binding pocket, the pyrrolidine-binding pocket, and the Tyr-rich hydrophobic channel.
2015 · Figshare · 0 citations
https://doi.org/10.1371/journal.pone.0107432.g010
Synthesis of 9: Reagents and conditions: (a) <i>p</i>-TsOH (cat), DMF, 60°C, 2 h, 70%; (b) 4-phenyl butyl bromide, K<sub>2</sub>CO<sub>3</sub>, DMF, 80°C, 2 h, 90%; (c) 1,4-dioxane, 4N HCl, reflux, 2 h, 85%.
2015 · Figshare · 0 citations
https://doi.org/10.1371/journal.pone.0107432.g006
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