Identification of ADAM10 as a major source of HER2 ectodomain sheddase activity in HER2 overexpressing breast cancer cells
2006 · Cancer Biology & Therapy · 184 citations
https://doi.org/10.4161/cbt.5.6.2708
D
Ding‐Quan Qian
Claim or correct this author profile
Claim this profile or suggest corrections to the name, affiliation, bio, photo, or paper titles. Approved changes appear as verified CitedEvidence overlays.
41
Papers
518
Citations
11
h-index
13
i10-index
Ding‐Quan Qian is an academic researcher from Incyte (United States). The author has contributed to research in topics: Crystallization and Solubility Studies & X-ray Diffraction in Crystallography & Synthesis and Reactivity of Sulfur-Containing Compounds. The author has an h-index of 11, co-authored 35 publications.
Papers by this author
worksDesign and identification of selective HER-2 sheddase inhibitors via P1′ manipulation and unconventional P2′ perturbations to induce a molecular metamorphosis
2007 · Bioorganic & Medicinal Chemistry Letters · 8 citations
https://doi.org/10.1016/j.bmcl.2007.10.108
Compelling P1 substituent affect on metalloprotease binding profile enables the design of a novel cyclohexyl core scaffold with excellent MMP selectivity and HER-2 sheddase inhibition
2009 · Bioorganic & Medicinal Chemistry Letters · 4 citations
https://doi.org/10.1016/j.bmcl.2009.04.143
Corrigendum to “Compelling P1 substituent affect on metalloprotease binding profile enables the design of a novel cyclohexyl core scaffold with excellent MMP selectivity and HER-2 sheddase inhibition” [Bioorg. Med. Chem. Lett. 19 (2009) 3525]
2009 · Bioorganic & Medicinal Chemistry Letters · 1 citations
https://doi.org/10.1016/j.bmcl.2009.08.015
Research topics
topicsChat about Author
Papers
Chat
Click to start Chat