Treatment with HC-070, a potent inhibitor of TRPC4 and TRPC5, leads to anxiolytic and antidepressant effects in mice
2018 · PLoS ONE · 135 citations
https://doi.org/10.1371/journal.pone.0191225
S
Stefan Just
Claim or correct this author profile
Claim this profile or suggest corrections to the name, affiliation, bio, photo, or paper titles. Approved changes appear as verified CitedEvidence overlays.
31
Papers
702
Citations
14
h-index
20
i10-index
Stefan Just is an academic researcher from Boehringer Ingelheim (Germany). The author has contributed to research in topics: Pain Mechanisms and Treatments & Neuropeptides and Animal Physiology & Migraine and Headache Studies. The author has an h-index of 14, co-authored 27 publications.
Papers by this author
worksThe effects of transient receptor potential cation channel inhibition by BI 1358894 on cortico-limbic brain reactivity to negative emotional stimuli in major depressive disorder
2022 · European Neuropsychopharmacology · 19 citations
https://doi.org/10.1016/j.euroneuro.2022.10.009
Somatostatin Receptor 4 Agonism Normalizes Stress-Related Excessive Amygdala Glutamate Release and Pavlovian Aversion Learning and Memory in Rodents
2021 · Biological Psychiatry Global Open Science · 14 citations
https://doi.org/10.1016/j.bpsgos.2021.11.006
Effect of BI 1358894 on Cholecystokinin-Tetrapeptide (CCK-4)-Induced Anxiety, Panic Symptoms, and Stress Biomarkers: A Phase I Randomized Trial in Healthy Males
2023 · CNS Drugs · 12 citations
https://doi.org/10.1007/s40263-023-01042-3
Efficacy, Tolerability, and Safety of TRPC4/5 Inhibitor BI 1358894 in Patients With Major Depressive Disorder and Inadequate Response to Antidepressants
2025 · The Journal of Clinical Psychiatry · 0 citations
https://doi.org/10.4088/jcp.25m15868
Research topics
topicsChat about Author
Papers
Chat
Click to start Chat