MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens
2014 · Genome biology · 2,635 citations
https://doi.org/10.1186/s13059-014-0554-4
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Han Xu is an academic researcher from The University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: CRISPR and Genetic Engineering & RNA and protein synthesis mechanisms & RNA modifications and cancer. The author has an h-index of 34, co-authored 75 publications.
ORCID: 0000-0002-8654-461XPapers by this author
worksComputational correction of copy number effect improves specificity of CRISPR–Cas9 essentiality screens in cancer cells
2017 · Nature Genetics · 2,117 citations
https://doi.org/10.1038/ng.3984
ChiLin: a comprehensive ChIP-seq and DNase-seq quality control and analysis pipeline
2016 · BMC Bioinformatics · 135 citations
https://doi.org/10.1186/s12859-016-1274-4
De novo identification of essential protein domains from CRISPR-Cas9 tiling-sgRNA knockout screens
2019 · Nature Communications · 75 citations
https://doi.org/10.1038/s41467-019-12489-8
PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade
2022 · Cell Reports · 55 citations
https://doi.org/10.1016/j.celrep.2022.110582
Systematic functional interrogation of human pseudogenes using CRISPRi
2021 · Genome biology · 32 citations
https://doi.org/10.1186/s13059-021-02464-2
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