Reductive carboxylation supports redox homeostasis during anchorage-independent growth
2016 · Nature · 582 citations
https://doi.org/10.1038/nature17393
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Lei Jiang
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Lei Jiang is an academic researcher from Tianjin University of Traditional Chinese Medicine. The author has contributed to research in topics: Cancer, Hypoxia, and Metabolism & Adipose Tissue and Metabolism & Mitochondrial Function and Pathology. The author has an h-index of 33, co-authored 99 publications.
ORCID: 0000-0002-8596-556XPapers by this author
worksOxidation of Alpha-Ketoglutarate Is Required for Reductive Carboxylation in Cancer Cells with Mitochondrial Defects
2014 · Cell Reports · 334 citations
https://doi.org/10.1016/j.celrep.2014.04.037
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1–AMPK signalling
2015 · Nature Cell Biology · 277 citations
https://doi.org/10.1038/ncb3255
Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans
2019 · Cell Reports · 117 citations
https://doi.org/10.1016/j.celrep.2019.04.005
Mitochondrial division inhibitor (mdivi-1) decreases oxidative metabolism in cancer
2020 · British Journal of Cancer · 103 citations
https://doi.org/10.1038/s41416-020-0778-x
An updated HACOR score for predicting the failure of noninvasive ventilation: a multicenter prospective observational study
2022 · Critical Care · 76 citations
https://doi.org/10.1186/s13054-022-04060-7
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