Senolytic CAR T cells reverse senescence-associated pathologies
2020 · Nature · 986 citations
https://doi.org/10.1038/s41586-020-2403-9
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Jacob A. Boyer
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Jacob A. Boyer is an academic researcher from Ludwig Cancer Research. The author has contributed to research in topics: FOXO transcription factor regulation & PI3K/AKT/mTOR signaling in cancer & Melanoma and MAPK Pathways. The author has an h-index of 10, co-authored 59 publications.
ORCID: 0000-0001-5651-2337Papers by this author
worksP-selectin-targeted nanocarriers induce active crossing of the blood–brain barrier via caveolin-1-dependent transcytosis
2023 · Nature Materials · 191 citations
https://doi.org/10.1038/s41563-023-01481-9
Prophylactic and long-lasting efficacy of senolytic CAR T cells against age-related metabolic dysfunction
2024 · Nature Aging · 148 citations
https://doi.org/10.1038/s43587-023-00560-5
Aryl Hydrocarbon Receptor Activation Synergistically Induces Lipopolysaccharide-Mediated Expression of Proinflammatory Chemokine (c–c motif) Ligand 20
2015 · Toxicological Sciences · 35 citations
https://doi.org/10.1093/toxsci/kfv178
Editor’s Highlight: Ah Receptor Activation Potentiates Neutrophil Chemoattractant (C-X-C Motif) Ligand 5 Expression in Keratinocytes and Skin
2017 · Toxicological Sciences · 31 citations
https://doi.org/10.1093/toxsci/kfx160
Combined inhibition of KRASG12C and mTORC1 kinase is synergistic in non-small cell lung cancer
2024 · Nature Communications · 25 citations
https://doi.org/10.1038/s41467-024-50063-z
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