Efficient evolution of human antibodies from general protein language models
2023 · Nature Biotechnology · 410 citations
https://doi.org/10.1038/s41587-023-01763-2
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Theodora U. J. Bruun
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Theodora U. J. Bruun is an academic researcher from University of Chicago. The author has contributed to research in topics: HIV Research and Treatment & SARS-CoV-2 and COVID-19 Research & Metabolism and Genetic Disorders. The author has an h-index of 14, co-authored 33 publications.
ORCID: 0000-0002-7462-2537Papers by this author
worksEngineering a Rugged Nanoscaffold To Enhance Plug-and-Display Vaccination
2018 · ACS Nano · 290 citations
https://doi.org/10.1021/acsnano.8b02805
Unsupervised evolution of protein and antibody complexes with a structure-informed language model
2024 · Science · 113 citations
https://doi.org/10.1126/science.adk8946
Multilayered HIV-1 resistance in HSPCs through CCR5 Knockout and B cell secretion of HIV-inhibiting antibodies
2025 · Nature Communications · 9 citations
https://doi.org/10.1038/s41467-025-58371-8
Structure-guided stabilization improves the ability of the HIV-1 gp41 hydrophobic pocket to elicit neutralizing antibodies
2023 · Journal of Biological Chemistry · 7 citations
https://doi.org/10.1016/j.jbc.2023.103062
A broad antibody with enhanced HIV-1 neutralization via bispecific antibody-mediated prepositioning
2025 · Nature Communications · 4 citations
https://doi.org/10.1038/s41467-025-60035-6
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