A large-scale chemical modification screen identifies design rules to generate siRNAs with high activity, high stability and low toxicity
2009 · Nucleic Acids Research · 349 citations
https://doi.org/10.1093/nar/gkp106
J
Jesper Wengel
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Jesper Wengel is an academic researcher from University of Southern Denmark. The author has contributed to research in topics: DNA and Nucleic Acid Chemistry & Advanced biosensing and bioanalysis techniques & RNA Interference and Gene Delivery. The author has an h-index of 62, co-authored 499 publications.
ORCID: 0000-0001-9835-1009Papers by this author
worksUNA (unlocked nucleic acid): A flexible RNA mimic that allows engineering of nucleic acid duplex stability
2009 · Bioorganic & Medicinal Chemistry · 143 citations
https://doi.org/10.1016/j.bmc.2009.06.045
Locked nucleic acid as a novel class of therapeutic agents
2009 · RNA Biology · 122 citations
https://doi.org/10.4161/rna.6.3.8807
Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets.
2006 · BMC Molecular Biology · 42 citations
https://doi.org/10.1186/1471-2199-7-19
The Advantages of Being Locked
2007 · Journal of Biological Chemistry · 37 citations
https://doi.org/10.1074/jbc.m706993200
Improved Cancer Targeting by Multimerizing Aptamers on Nanoscaffolds
2020 · Molecular Therapy — Nucleic Acids · 29 citations
https://doi.org/10.1016/j.omtn.2020.10.013
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