Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure
2017 · Nature · 196 citations
https://doi.org/10.1038/nature23652
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Alem W. Kahsai
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Alem W. Kahsai is an academic researcher from Duke Medical Center. The author has contributed to research in topics: Receptor Mechanisms and Signaling & Neuropeptides and Animal Physiology & Mass Spectrometry Techniques and Applications. The author has an h-index of 26, co-authored 38 publications.
ORCID: 0000-0001-9272-4484Papers by this author
worksMechanism of β <sub>2</sub> AR regulation by an intracellular positive allosteric modulator
2019 · Science · 130 citations
https://doi.org/10.1126/science.aaw8981
Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling
2017 · Nature Communications · 114 citations
https://doi.org/10.1038/ncomms14335
GPCR-mediated β-arrestin activation deconvoluted with single-molecule precision
2022 · Cell · 105 citations
https://doi.org/10.1016/j.cell.2022.03.042
Small-Molecule Positive Allosteric Modulators of the β2-Adrenoceptor Isolated from DNA-Encoded Libraries
2018 · Molecular Pharmacology · 90 citations
https://doi.org/10.1124/mol.118.111948
Mechanism of beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy
2024 · bioRxiv (Cold Spring Harbor Laboratory) · 4 citations
https://doi.org/10.1101/2024.07.31.605623
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