INTELLANCE 2/EORTC 1410 randomized phase II study of Depatux-M alone and with temozolomide vs temozolomide or lomustine in recurrent EGFR amplified glioblastoma
2019 · Neuro-Oncology · 184 citations
https://doi.org/10.1093/neuonc/noz222
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Juan Manuel Sepúlveda-Sánchez
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Juan Manuel Sepúlveda-Sánchez is an academic researcher from Universidad de Santiago de Chile. The author has contributed to research in topics: Glioma Diagnosis and Treatment & Brain Metastases and Treatment & Radiomics and Machine Learning in Medical Imaging. The author has an h-index of 40, co-authored 377 publications.
ORCID: 0000-0003-3548-9961Papers by this author
worksCardiac Safety of TGF-β Receptor I Kinase Inhibitor LY2157299 Monohydrate in Cancer Patients in a First-in-Human Dose Study
2014 · Cardiovascular Toxicology · 109 citations
https://doi.org/10.1007/s12012-014-9297-4
Pharmacokinetic, pharmacodynamic and biomarker evaluation of transforming growth factor-β receptor I kinase inhibitor, galunisertib, in phase 1 study in patients with advanced cancer
2014 · Investigational New Drugs · 104 citations
https://doi.org/10.1007/s10637-014-0192-4
Stratification of radiosensitive brain metastases based on an actionable S100A9/RAGE resistance mechanism
2022 · Nature Medicine · 78 citations
https://doi.org/10.1038/s41591-022-01749-8
A Phase Ib/II, open-label, multicenter study of INC280 (capmatinib) alone and in combination with buparlisib (BKM120) in adult patients with recurrent glioblastoma
2019 · Journal of Neuro-Oncology · 49 citations
https://doi.org/10.1007/s11060-019-03337-2
A clinically compatible drug‐screening platform based on organotypic cultures identifies vulnerabilities to prevent and treat brain metastasis
2022 · EMBO Molecular Medicine · 34 citations
https://doi.org/10.15252/emmm.202114552
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