KRAS interaction with RAF1 RAS-binding domain and cysteine-rich domain provides insights into RAS-mediated RAF activation
2021 · Nature Communications · 241 citations
https://doi.org/10.1038/s41467-021-21422-x
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Lucy C. Young
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Lucy C. Young is an academic researcher from University of California, San Francisco. The author has contributed to research in topics: Protein Tyrosine Phosphatases & Protein Kinase Regulation and GTPase Signaling & Microtubule and mitosis dynamics. The author has an h-index of 13, co-authored 21 publications.
ORCID: 0000-0003-2703-2347Papers by this author
worksSHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers
2019 · Nature Communications · 80 citations
https://doi.org/10.1038/s41467-019-10367-x
Light Acts on the Zebrafish Circadian Clock to Suppress Rhythmic Mitosis and Cell Proliferation
2012 · Journal of Biological Rhythms · 38 citations
https://doi.org/10.1177/0748730412440861
Structure of SHOC2-KRAS-PP1C complex reveals RAS isoform-specific determinants and insights into targeting complex assembly by RAS inhibitors
2026 · Nature Communications · 0 citations
https://doi.org/10.1038/s41467-026-68319-1
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